A clinicopathological study on verrucous hyperplasia and verrucous carcinoma of the oral mucosa.
J Oral Pathol Med
; 41(2): 131-5, 2012 Feb.
Article
in En
| MEDLINE
| ID: mdl-21913992
ABSTRACT
BACKGROUND:
Oral verrucous hyperplasia (VH) and verrucous carcinoma (VC) are two clinicopathologically distinctive oral verrucous lesions. The objective of this study was to investigate the clinicopathological features of the two verrucous lesions and estimate their relationship from China.METHODS:
Retrospective review of two series of patients with histologically confirmed VH (n = 121) and VC (n = 56) between 1996 and 2009 in our hospital were conducted.RESULTS:
The average age of VH was 58.5 years (ratio malefemale = 1.37) with the tongue being the predominant site. The average age of VC was 64.3 years (ratio malefemale = 1.15) with the lower lip being the predominant site. Multivariate analysis revealed that the elderly patient with verrucous lesion (≥60 years) was associated with 3.06-fold (P = 0.007) increased carcinoma risk compared with the non-elderly patient. The lesion located on lower lip was associated with 13.54-fold (P < 0.001) increased carcinoma risk compared with other sites.CONCLUSION:
Clinicopathological features of VH and VC in China were elucidated. Elderly patient with oral verrucous lesion located on the lower lip correlates with higher risk of carcinoma.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Precancerous Conditions
/
Mouth Neoplasms
/
Carcinoma, Verrucous
/
Mouth Mucosa
Type of study:
Etiology_studies
/
Observational_studies
/
Risk_factors_studies
Limits:
Adult
/
Aged
/
Aged80
/
Female
/
Humans
/
Male
/
Middle aged
Country/Region as subject:
Asia
Language:
En
Journal:
J Oral Pathol Med
Journal subject:
ODONTOLOGIA
/
PATOLOGIA
Year:
2012
Document type:
Article
Affiliation country:
China