Monoclonal antibody 2-152a suppresses hepatitis C virus infection through betaine/GABA transporter-1.

Satoh, Masaaki; Saito, Makoto; Takano, Takashi; Kasama, Yuri; Nishimura, Tomohiro; Nishito, Yasumasa; Hirata, Yuichi; Arai, Masaaki; Sudoh, Masayuki; Kai, Chieko; Kohara, Michinori; Tsukiyama-Kohara, Kyoko

Satoh, Masaaki; Saito, Makoto; Takano, Takashi; Kasama, Yuri; Nishimura, Tomohiro; Nishito, Yasumasa; Hirata, Yuichi; Arai, Masaaki; Sudoh, Masayuki; Kai, Chieko; Kohara, Michinori; Tsukiyama-Kohara, Kyoko.

Affiliation

Satoh M; Department of Experimental Phylaxiology, Faculty of Life Sciences, Kumamoto University, Honjo Kumamoto City, Japan.

J Infect Dis ; 204(8): 1172-80, 2011 Oct 15.

Article in En | MEDLINE | ID: mdl-21917889

Subject(s)

Antibodies, Monoclonal/therapeutic use; Carrier Proteins/metabolism; GABA Plasma Membrane Transport Proteins/metabolism; Hepacivirus/physiology; Hepatitis C, Chronic/drug therapy; Virus Replication/drug effects; Animals; Antibodies, Monoclonal/immunology; Cell Line, Tumor; GABA Plasma Membrane Transport Proteins/genetics; Hep G2 Cells; Hepatitis C, Chronic/metabolism; Hepatitis C, Chronic/virology; Humans; Mice; Mice, Inbred BALB C; Mice, Transgenic; Nerve Tissue Proteins/immunology; Oligonucleotide Array Sequence Analysis; Oxidoreductases Acting on CH-CH Group Donors/immunology; RNA/chemistry; RNA/genetics; RNA Interference; Reverse Transcriptase Polymerase Chain Reaction

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Virus Replication / Carrier Proteins / Hepacivirus / Hepatitis C, Chronic / GABA Plasma Membrane Transport Proteins / Antibodies, Monoclonal Limits: Animals / Humans Language: En Journal: J Infect Dis Year: 2011 Document type: Article Affiliation country: Japan Country of publication: United States

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