Loss of Akt1 evokes epithelial-mesenchymal transition by autocrine regulation of transforming growth factor-ß1.

Kim, Eun Kyoung; Yun, Sung Ji; Ha, Jung Min; Kim, Young Whan; Jin, In Hye; Woo, Dae Han; Song, Sang Hun; Ha, Hong Koo; Choi, Yoon Sup; Lee, Taehoon G; Bae, Sun Sik

Kim, Eun Kyoung; Yun, Sung Ji; Ha, Jung Min; Kim, Young Whan; Jin, In Hye; Woo, Dae Han; Song, Sang Hun; Ha, Hong Koo; Choi, Yoon Sup; Lee, Taehoon G; Bae, Sun Sik.

Affiliation

Kim EK; MRC for Ischemic Tissue Regeneration, Medical Research Institute, Department of Pharmacology, School of Medicine, Pusan National University, Bumeo-ri, Mulgeum-eup, Yangsan-si, Yangsan, Kyungnam 626-870, Republic of Korea.

Adv Biol Regul ; 52(1): 88-96, 2012 Jan.

Article in En | MEDLINE | ID: mdl-21925532

Subject(s)

Epithelial-Mesenchymal Transition/physiology; Proto-Oncogene Proteins c-akt/metabolism; Transforming Growth Factor beta1/metabolism; Blotting, Western; Cell Line, Tumor; Cell Movement/genetics; Cell Movement/physiology; Epithelial-Mesenchymal Transition/genetics; Gene Silencing/physiology; Humans; Immunohistochemistry; Proto-Oncogene Proteins c-akt/genetics; Transforming Growth Factor beta1/genetics

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Collection: 01-internacional Database: MEDLINE Main subject: Proto-Oncogene Proteins c-akt / Transforming Growth Factor beta1 / Epithelial-Mesenchymal Transition Limits: Humans Language: En Journal: Adv Biol Regul Year: 2012 Document type: Article Country of publication: United kingdom

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