Revisiting the rule of five on the basis of pharmacokinetic data from rat.

Ridder, Lars; Wang, Hongwu; de Vlieg, Jacob; Wagener, Markus

Ridder, Lars; Wang, Hongwu; de Vlieg, Jacob; Wagener, Markus.

Affiliation

Ridder L; Molecular Design and Informatics, Merck Research Laboratories, Molenstraat 110, 5342 CC Oss, The Netherlands. lars.ridder@yahoo.com

ChemMedChem ; 6(11): 1967-70, 2011 Nov 04.

Article in En | MEDLINE | ID: mdl-21932224

Subject(s)

Models, Biological; Pharmaceutical Preparations/administration & dosage; Pharmacokinetics; Structure-Activity Relationship; Administration, Oral; Animals; Biological Availability; Chemical Phenomena; Gonadotropins/administration & dosage; Gonadotropins/chemistry; Gonadotropins/pharmacokinetics; Pharmaceutical Preparations/chemistry; Rats

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Structure-Activity Relationship / Pharmacokinetics / Pharmaceutical Preparations / Models, Biological Limits: Animals Language: En Journal: ChemMedChem Journal subject: FARMACOLOGIA / QUIMICA Year: 2011 Document type: Article Affiliation country: Netherlands

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