LC- and CZE-ICP-MS approaches for the in vivo analysis of the anticancer drug candidate sodium trans-[tetrachloridobis(1H-indazole)ruthenate(III)] (KP1339) in mouse plasma.

Bytzek, Anna K; Boeck, Katharina; Hermann, Gerrit; Hann, Stephan; Keppler, Bernhard K; Hartinger, Christian G; Koellensperger, Gunda

Bytzek, Anna K; Boeck, Katharina; Hermann, Gerrit; Hann, Stephan; Keppler, Bernhard K; Hartinger, Christian G; Koellensperger, Gunda.

Affiliation

Bytzek AK; University of Vienna, Institute of Inorganic Chemistry, Waehringer Str. 42, A-1090 Vienna, Austria.

Metallomics ; 3(10): 1049-55, 2011 Oct.

Article in En | MEDLINE | ID: mdl-21935553

Subject(s)

Antineoplastic Agents/blood; Chromatography, Gel/methods; Electrophoresis, Capillary/methods; Mass Spectrometry/methods; Organometallic Compounds/blood; Animals; Antineoplastic Agents/metabolism; Indazoles/blood; Indazoles/metabolism; Limit of Detection; Mice; Organometallic Compounds/metabolism; Protein Binding; Ruthenium/blood; Ruthenium/metabolism; Serum Albumin/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Organometallic Compounds / Mass Spectrometry / Chromatography, Gel / Electrophoresis, Capillary / Antineoplastic Agents Type of study: Evaluation_studies Limits: Animals Language: En Journal: Metallomics Journal subject: BIOQUIMICA Year: 2011 Document type: Article Affiliation country: Austria

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