Noxa induces apoptosis in oncogene-expressing cells through catch-and-release mechanism operating between Puma and Mcl-1.

Nakajima, Wataru; Tanaka, Nobuyuki

Nakajima, Wataru; Tanaka, Nobuyuki.

Affiliation

Nakajima W; Department of Molecular Oncology, Institute of Gerontology, Nippon Medical School, 1-396 Kosugi-cho, Nakahara-ku, Kawasaki 211-8533, Japan.

Biochem Biophys Res Commun ; 413(4): 643-8, 2011 Oct 07.

Article in En | MEDLINE | ID: mdl-21945433

Subject(s)

Adenovirus E1A Proteins/genetics; Apoptosis Regulatory Proteins/metabolism; Apoptosis/genetics; Oncogenes; Proto-Oncogene Proteins c-bcl-2/metabolism; Proto-Oncogene Proteins c-bcl-2/physiology; Tumor Suppressor Proteins/metabolism; Animals; DNA Damage; Gene Knockdown Techniques; Mice; Mice, Mutant Strains; Mitochondria/genetics; Mitochondria/metabolism; Myeloid Cell Leukemia Sequence 1 Protein; Proto-Oncogene Proteins c-bcl-2/genetics; Tumor Suppressor Protein p53/genetics; Tumor Suppressor Protein p53/metabolism; bcl-2 Homologous Antagonist-Killer Protein/metabolism; bcl-2-Associated X Protein/metabolism

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Oncogenes / Apoptosis / Adenovirus E1A Proteins / Proto-Oncogene Proteins c-bcl-2 / Tumor Suppressor Proteins / Apoptosis Regulatory Proteins Limits: Animals Language: En Journal: Biochem Biophys Res Commun Year: 2011 Document type: Article Affiliation country: Japan

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google