Contributions of A2A and A2B adenosine receptors in coronary flow responses in relation to the KATP channel using A2B and A2A/2B double-knockout mice.

Sanjani, Maryam Sharifi; Teng, Bunyen; Krahn, Thomas; Tilley, Stephen; Ledent, Catherine; Mustafa, S Jamal

Sanjani, Maryam Sharifi; Teng, Bunyen; Krahn, Thomas; Tilley, Stephen; Ledent, Catherine; Mustafa, S Jamal.

Affiliation

Sanjani MS; Department of Physiology and Pharmacology, Center for Cardiovascular Respiratory Sciences, West Virginia University, Morgantown, USA.

Am J Physiol Heart Circ Physiol ; 301(6): H2322-33, 2011 Dec.

Article in En | MEDLINE | ID: mdl-21949117

Subject(s)

Coronary Circulation; Coronary Vessels/metabolism; KATP Channels/metabolism; Receptor, Adenosine A2A/deficiency; Receptor, Adenosine A2B/deficiency; Vasodilation; Animals; Arterioles/metabolism; Blood Flow Velocity; Coronary Circulation/drug effects; Coronary Vessels/drug effects; Dose-Response Relationship, Drug; Heart Rate; KATP Channels/antagonists & inhibitors; Mesentery/blood supply; Mice; Mice, Inbred C57BL; Mice, Knockout; Perfusion; Potassium Channel Blockers/pharmacology; Purinergic P1 Receptor Agonists/pharmacology; Purinergic P1 Receptor Antagonists/pharmacology; Receptor, Adenosine A2A/genetics; Receptor, Adenosine A2B/genetics; Vasodilation/drug effects; Ventricular Function, Left; Ventricular Pressure

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Vasodilation / Coronary Circulation / Coronary Vessels / Receptor, Adenosine A2A / Receptor, Adenosine A2B / KATP Channels Limits: Animals Language: En Journal: Am J Physiol Heart Circ Physiol Journal subject: CARDIOLOGIA / FISIOLOGIA Year: 2011 Document type: Article Affiliation country: United States Country of publication: United States

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