Persistent ocular motor manifestations and related visual consequences in multiple sclerosis.
Ann N Y Acad Sci
; 1233: 327-34, 2011 Sep.
Article
in En
| MEDLINE
| ID: mdl-21951012
ABSTRACT
Abnormal eye movements in multiple sclerosis (MS) are often persistent and known to be associated with general disability. However, there is no precise knowledge concerning their incidence and resulting visual handicap. The aim of our study was to describe the persistent ocular motor manifestations in MS and relate them to visual functions tested with visual acuity and with a vision-related questionnaire. We selected 24 MS patients complaining of persistent visual disability associated with ocular motor manifestations without any anterior visual pathway deficit. Internuclear ophthalmoplegia was the most frequently observed symptom, followed by gaze-evoked nystagmus, saccadic hypermetria, and then pendular nystagmus. Pendular nystagmus, saccadic hypermetria, and the association of internuclear ophthalmoplegia and gaze-evoked nystagmus were associated with decreased visual acuity and visual functional scores. There was a correlation between the number of abnormal eye movements and visual functions. This study demonstrates that ocular motor dysfunction in MS induces specific visual dysfunction and handicap.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Ocular Motility Disorders
/
Multiple Sclerosis
Type of study:
Etiology_studies
Limits:
Adult
/
Female
/
Humans
/
Male
/
Middle aged
Language:
En
Journal:
Ann N Y Acad Sci
Year:
2011
Document type:
Article
Affiliation country:
France