Inhibition of autophagy by 3-methyladenine protects 1321N1 astrocytoma cells against pyocyanin- and 1-hydroxyphenazine-induced toxicity.

McFarland, Amelia J; Anoopkumar-Dukie, Shailendra; Perkins, Anthony V; Davey, Andrew K; Grant, Gary D

McFarland, Amelia J; Anoopkumar-Dukie, Shailendra; Perkins, Anthony V; Davey, Andrew K; Grant, Gary D.

Affiliation

McFarland AJ; Griffith Health Institute, Griffith University, Gold Coast, QLD, Australia.

Arch Toxicol ; 86(2): 275-84, 2012 Feb.

Article in En | MEDLINE | ID: mdl-21964636

Subject(s)

Adenine/analogs & derivatives; Astrocytes/drug effects; Phenazines/toxicity; Pyocyanine/toxicity; Adenine/pharmacology; Antioxidants/metabolism; Apoptosis/drug effects; Astrocytes/cytology; Astrocytes/metabolism; Astrocytoma; Autophagy/drug effects; Cell Line, Tumor; Cells, Cultured; Cellular Senescence/drug effects; Drug Interactions; Humans; Oxidative Stress/drug effects; Reactive Oxygen Species/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Phenazines / Pyocyanine / Adenine / Astrocytes Limits: Humans Language: En Journal: Arch Toxicol Year: 2012 Document type: Article Affiliation country: Australia

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