Simultaneous determination of nitrendipine and hydrochlorothiazide in spontaneously hypertensive rat plasma using HPLC with on-line solid-phase extraction.

Shang, Dewei; Wang, Xipei; Zhao, Xiutai; Huang, Fengming; Tian, Ganzhong; Lu, Wei; Zhou, Tianyan

Shang, Dewei; Wang, Xipei; Zhao, Xiutai; Huang, Fengming; Tian, Ganzhong; Lu, Wei; Zhou, Tianyan.

Affiliation

Shang D; The State Key Laboratory of Natural and Biomimetic Drugs, Peking University, Beijing, China.

J Chromatogr B Analyt Technol Biomed Life Sci ; 879(30): 3459-64, 2011 Nov 15.

Article in En | MEDLINE | ID: mdl-21968134

Subject(s)

Chromatography, High Pressure Liquid/methods; Hydrochlorothiazide/blood; Hypertension/blood; Nitrendipine/blood; Solid Phase Extraction/methods; Animals; Area Under Curve; Drug Stability; Hydrochlorothiazide/pharmacokinetics; Least-Squares Analysis; Nitrendipine/pharmacokinetics; Rats; Rats, Inbred SHR; Reproducibility of Results; Sensitivity and Specificity; Temperature

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Nitrendipine / Chromatography, High Pressure Liquid / Solid Phase Extraction / Hydrochlorothiazide / Hypertension Type of study: Diagnostic_studies / Prognostic_studies Limits: Animals Language: En Journal: J Chromatogr B Analyt Technol Biomed Life Sci Journal subject: ENGENHARIA BIOMEDICA Year: 2011 Document type: Article Affiliation country: China Country of publication: Netherlands

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