Nitric oxide and hypoxia exacerbate alcohol-induced mitochondrial dysfunction in hepatocytes.

Zelickson, Blake R; Benavides, Gloria A; Johnson, Michelle S; Chacko, Balu K; Venkatraman, Aparna; Landar, Aimee; Betancourt, Angela M; Bailey, Shannon M; Darley-Usmar, Victor M

Zelickson, Blake R; Benavides, Gloria A; Johnson, Michelle S; Chacko, Balu K; Venkatraman, Aparna; Landar, Aimee; Betancourt, Angela M; Bailey, Shannon M; Darley-Usmar, Victor M.

Affiliation

Zelickson BR; Center for Free Radical Biology, University of Alabama at Birmingham, AL 35294, USA.

Biochim Biophys Acta ; 1807(12): 1573-82, 2011 Dec.

Article in En | MEDLINE | ID: mdl-21971515

Subject(s)

Ethanol/pharmacology; Hepatocytes/metabolism; Hypoxia/metabolism; Mitochondria, Liver/drug effects; Mitochondria, Liver/physiology; Nitric Oxide/metabolism; Animals; Cell Respiration/drug effects; Cell Respiration/physiology; Diet; Energy Metabolism/drug effects; Ethanol/administration & dosage; Hepatocytes/cytology; Liver/drug effects; Liver/metabolism; Liver/pathology; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Nitric Oxide Synthase Type II/genetics; Nitric Oxide Synthase Type II/metabolism; Rats; Rats, Sprague-Dawley

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Mitochondria, Liver / Hepatocytes / Ethanol / Hypoxia / Nitric Oxide Limits: Animals Language: En Journal: Biochim Biophys Acta Year: 2011 Document type: Article Affiliation country: United States Country of publication: Netherlands

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