The effect of intrathecal mu, delta, kappa, and alpha-2 agonists on thermal hyperalgesia induced by mild burn on hind paw in rats.

Kim, Hyun Jung; Seol, Tae Kyung; Lee, Hee Jong; Yaksh, Tony L; Jun, Jong Hun

Kim, Hyun Jung; Seol, Tae Kyung; Lee, Hee Jong; Yaksh, Tony L; Jun, Jong Hun.

Affiliation

Kim HJ; Department of Anesthesiology and Pain Medicine, Jeju National University College of Medicine, Jeju, Republic of Korea.

J Anesth ; 25(6): 884-91, 2011 Dec.

Article in En | MEDLINE | ID: mdl-21983967

Subject(s)

Adrenergic alpha-2 Receptor Agonists/pharmacology; Hyperalgesia/drug therapy; Receptors, Opioid, delta/agonists; Receptors, Opioid, kappa/agonists; Receptors, Opioid, mu/agonists; 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer/pharmacology; Animals; Burns/complications; Burns/drug therapy; Clonidine/analogs & derivatives; Clonidine/pharmacology; Enkephalin, D-Penicillamine (2,5)-/pharmacology; Hyperalgesia/etiology; Male; Morphine/pharmacology; Pain Threshold/drug effects; Random Allocation; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta/administration & dosage; Receptors, Opioid, kappa/administration & dosage; Receptors, Opioid, mu/administration & dosage; Spinal Cord/drug effects

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Receptors, Opioid, delta / Receptors, Opioid, kappa / Receptors, Opioid, mu / Adrenergic alpha-2 Receptor Agonists / Hyperalgesia Type of study: Etiology_studies / Prognostic_studies Limits: Animals Language: En Journal: J Anesth Journal subject: ANESTESIOLOGIA Year: 2011 Document type: Article Country of publication: Japan

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