Double-strand break-induced transcriptional silencing is associated with loss of tri-methylation at H3K4.

Seiler, Doris M; Rouquette, Jacques; Schmid, Volker J; Strickfaden, Hilmar; Ottmann, Christian; Drexler, Guido A; Mazurek, Belinda; Greubel, Christoph; Hable, Volker; Dollinger, Günther; Cremer, Thomas; Friedl, Anna A

Seiler, Doris M; Rouquette, Jacques; Schmid, Volker J; Strickfaden, Hilmar; Ottmann, Christian; Drexler, Guido A; Mazurek, Belinda; Greubel, Christoph; Hable, Volker; Dollinger, Günther; Cremer, Thomas; Friedl, Anna A.

Affiliation

Seiler DM; Department of Radiation Oncology, University Hospital of Munich, Schillerstr. 42, 80336, Munich, Germany.

Chromosome Res ; 19(7): 883-99, 2011 Oct.

Article in En | MEDLINE | ID: mdl-21987186

Subject(s)

Chromosomes/radiation effects; DNA Damage/radiation effects; Gene Silencing/radiation effects; Histones/metabolism; Protein Processing, Post-Translational/radiation effects; Cell Line, Tumor; Cell Nucleus/genetics; Cell Nucleus/metabolism; Cell Nucleus/radiation effects; Chromatin/chemistry; Chromatin/genetics; Chromosomes/chemistry; Chromosomes/genetics; DNA Breaks, Double-Stranded/radiation effects; Female; Fluorescent Antibody Technique; Gamma Rays/adverse effects; Histones/genetics; Humans; Methylation/radiation effects; Microscopy, Confocal; Osteosarcoma/genetics; Osteosarcoma/pathology; Protein Processing, Post-Translational/genetics; RNA Polymerase II/genetics; RNA Polymerase II/metabolism; Retinoblastoma-Binding Protein 2/genetics; Retinoblastoma-Binding Protein 2/metabolism; Uterine Cervical Neoplasms/genetics; Uterine Cervical Neoplasms/pathology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: DNA Damage / Histones / Protein Processing, Post-Translational / Chromosomes / Gene Silencing Type of study: Risk_factors_studies Limits: Female / Humans Language: En Journal: Chromosome Res Journal subject: BIOLOGIA MOLECULAR Year: 2011 Document type: Article Affiliation country: Germany

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