Regulation of ß2-adrenergic receptor maturation and anterograde trafficking by an interaction with Rab geranylgeranyltransferase: modulation of Rab geranylgeranylation by the receptor.

Lachance, Véronik; Cartier, Andréane; Génier, Samuel; Munger, Sandra; Germain, Pascale; Labrecque, Pascale; Parent, Jean-Luc

Lachance, Véronik; Cartier, Andréane; Génier, Samuel; Munger, Sandra; Germain, Pascale; Labrecque, Pascale; Parent, Jean-Luc.

Affiliation

Lachance V; Service de Rhumatologie, Département de Médecine, Faculté de Médecine et des Sciences de la Santé, Université de Sherbrooke, the Centre de Recherche Clinique Étienne-Le Bel, and the Institut de Pharmacologie de Sherbrooke, Sherbrooke, Québec, Canada J1H 5N4.

J Biol Chem ; 286(47): 40802-13, 2011 Nov 25.

Article in En | MEDLINE | ID: mdl-21990357

Subject(s)

Alkyl and Aryl Transferases/metabolism; Protein Prenylation; Receptors, Adrenergic, beta-2/metabolism; HEK293 Cells; HeLa Cells; Humans; Intracellular Space/metabolism; Mutagenesis, Site-Directed; Mutation; Protein Binding; Protein Structure, Tertiary; Protein Transport; Receptors, Adrenergic, beta-2/chemistry; Receptors, Adrenergic, beta-2/genetics; Substrate Specificity; rab GTP-Binding Proteins/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Protein Prenylation / Receptors, Adrenergic, beta-2 / Alkyl and Aryl Transferases Limits: Humans Language: En Journal: J Biol Chem Year: 2011 Document type: Article Country of publication: United States

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