Evidence-based guideline update: treatment of essential tremor: report of the Quality Standards subcommittee of the American Academy of Neurology.
Neurology
; 77(19): 1752-5, 2011 Nov 08.
Article
in En
| MEDLINE
| ID: mdl-22013182
ABSTRACT
BACKGROUND:
This evidence-based guideline is an update of the 2005 American Academy of Neurology practice parameter on the treatment of essential tremor (ET).METHODS:
A literature review using MEDLINE, EMBASE, Science Citation Index, and CINAHL was performed to identify clinical trials in patients with ET published between 2004 and April 2010. RESULTS ANDRECOMMENDATIONS:
Conclusions and recommendations for the use of propranolol, primidone (Level A, established as effective); alprazolam, atenolol, gabapentin (monotherapy), sotalol, topiramate (Level B, probably effective); nadolol, nimodipine, clonazepam, botulinum toxin A, deep brain stimulation, thalamotomy (Level C, possibly effective); and gamma knife thalamotomy (Level U, insufficient evidence) are unchanged from the previous guideline. Changes to conclusions and recommendations from the previous guideline include the following 1) levetiracetam and 3,4-diaminopyridine probably do not reduce limb tremor in ET and should not be considered (Level B); 2) flunarizine possibly has no effect in treating limb tremor in ET and may not be considered (Level C); and 3) there is insufficient evidence to support or refute the use of pregabalin, zonisamide, or clozapine as treatment for ET (Level U).
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Evidence-Based Medicine
/
Essential Tremor
/
Academies and Institutes
/
Research Report
/
Neurology
Type of study:
Diagnostic_studies
/
Guideline
/
Prognostic_studies
/
Systematic_reviews
Limits:
Humans
Country/Region as subject:
America do norte
Language:
En
Journal:
Neurology
Year:
2011
Document type:
Article
Affiliation country:
United States