Abnormal accumulation of autophagic vesicles correlates with axonal and synaptic pathology in young Alzheimer's mice hippocampus.

Sanchez-Varo, Raquel; Trujillo-Estrada, Laura; Sanchez-Mejias, Elisabeth; Torres, Manuel; Baglietto-Vargas, David; Moreno-Gonzalez, Ines; De Castro, Vanessa; Jimenez, Sebastian; Ruano, Diego; Vizuete, Marisa; Davila, Jose Carlos; Garcia-Verdugo, Jose Manuel; Jimenez, Antonio Jesus; Vitorica, Javier; Gutierrez, Antonia

Sanchez-Varo, Raquel; Trujillo-Estrada, Laura; Sanchez-Mejias, Elisabeth; Torres, Manuel; Baglietto-Vargas, David; Moreno-Gonzalez, Ines; De Castro, Vanessa; Jimenez, Sebastian; Ruano, Diego; Vizuete, Marisa; Davila, Jose Carlos; Garcia-Verdugo, Jose Manuel; Jimenez, Antonio Jesus; Vitorica, Javier; Gutierrez, Antonia.

Affiliation

Sanchez-Varo R; Dpto. Biología Celular, Genética y Fisiología, Facultad de Ciencias, Universidad de Málaga, Campus de Teatinos, 29071, Málaga, Spain.

Acta Neuropathol ; 123(1): 53-70, 2012 Jan.

Article in En | MEDLINE | ID: mdl-22020633

Subject(s)

Alzheimer Disease/pathology; Amyloid beta-Protein Precursor/metabolism; Axons/ultrastructure; Cytoplasmic Vesicles/ultrastructure; Hippocampus/ultrastructure; Neurites/ultrastructure; Plaque, Amyloid/ultrastructure; Alzheimer Disease/metabolism; Animals; Autophagy; Disease Models, Animal; Hippocampus/metabolism; Mice; Mice, Transgenic; Microscopy, Immunoelectron; Neurons/metabolism; Plaque, Amyloid/metabolism; Presynaptic Terminals/ultrastructure

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Axons / Neurites / Amyloid beta-Protein Precursor / Plaque, Amyloid / Cytoplasmic Vesicles / Alzheimer Disease / Hippocampus Limits: Animals Language: En Journal: Acta Neuropathol Year: 2012 Document type: Article Affiliation country: Spain Country of publication: Germany

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