Microbial production of phase I and phase II metabolites of midazolam.

Marvalin, Cyrille; Denoux, Mireille; Pérard, Serge; Roy, Sébastien; Azerad, Robert

Marvalin, Cyrille; Denoux, Mireille; Pérard, Serge; Roy, Sébastien; Azerad, Robert.

Affiliation

Marvalin C; Bertin Pharma, Parc d'Activités du Pas du Lac, Montigny-le-Bretonneux, France. robert.azerad@parisdescartes.fr

Xenobiotica ; 42(3): 285-93, 2012 Mar.

Article in En | MEDLINE | ID: mdl-22022919

Subject(s)

Beauveria/metabolism; Metabolic Detoxication, Phase II; Metabolic Detoxication, Phase I; Midazolam/metabolism; Streptomyces/metabolism; Beauveria/drug effects; Biotransformation/drug effects; Chromatography, Liquid; Esters/chemistry; Esters/metabolism; Glucuronides/chemistry; Glucuronides/metabolism; Humans; Magnetic Resonance Spectroscopy; Midazolam/analogs & derivatives; Midazolam/chemical synthesis; Midazolam/chemistry; Midazolam/pharmacology; Spectrometry, Mass, Electrospray Ionization; Streptomyces/drug effects

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Streptomyces / Midazolam / Metabolic Detoxication, Phase I / Metabolic Detoxication, Phase II / Beauveria Limits: Humans Language: En Journal: Xenobiotica Year: 2012 Document type: Article Affiliation country: France Country of publication: United kingdom

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