Prevalence of congenital myopathies in a representative pediatric united states population.
Ann Neurol
; 70(4): 662-5, 2011 Oct.
Article
in En
| MEDLINE
| ID: mdl-22028225
ABSTRACT
The prevalence of congenital myopathies in the United States has not been examined. To address this, we determined the point prevalence of congenital myopathies in a well-defined pediatric population from Southeastern Michigan. The overall point prevalence was 126,000. Mutations in RYR1 were the most common cause of congenital myopathies at 190,000. Our data broadly agrees with estimates from previous European studies and provides the first estimate of the prevalence of congenital myopathies in the United States. Ann Neurol 2011;70662-665.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Ryanodine Receptor Calcium Release Channel
/
Muscular Dystrophies
Type of study:
Prevalence_studies
/
Risk_factors_studies
Limits:
Child
/
Female
/
Humans
/
Male
Country/Region as subject:
America do norte
Language:
En
Journal:
Ann Neurol
Year:
2011
Document type:
Article
Affiliation country:
United States