Recent advances using FcRn overexpression in transgenic animals to overcome impediments of standard antibody technologies to improve the generation of specific antibodies.

Kacskovics, Imre; Cervenak, Judit; Erdei, Anna; Goldsby, Richard A; Butler, John E

Kacskovics, Imre; Cervenak, Judit; Erdei, Anna; Goldsby, Richard A; Butler, John E.

Affiliation

Kacskovics I; ImmunoGenes Ltd., Budakeszi, Hungary. kacskovics@immunogenes.com

MAbs ; 3(5): 431-9, 2011.

Article in En | MEDLINE | ID: mdl-22048692

Subject(s)

Antibodies, Monoclonal/biosynthesis; Histocompatibility Antigens Class I/metabolism; Immunoglobulin G/biosynthesis; Receptors, Fc/metabolism; Transgenes/physiology; Up-Regulation; Animals; Animals, Genetically Modified; Antibodies, Monoclonal/immunology; Biotechnology/methods; Guinea Pigs; Histocompatibility Antigens Class I/genetics; Humans; Immunoglobulin G/immunology; Mice; Rabbits; Receptors, Fc/genetics; Transgenes/genetics

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Immunoglobulin G / Receptors, Fc / Histocompatibility Antigens Class I / Up-Regulation / Transgenes / Antibodies, Monoclonal Limits: Animals / Humans Language: En Journal: MAbs Journal subject: ALERGIA E IMUNOLOGIA Year: 2011 Document type: Article Affiliation country: Hungary Country of publication: United States

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