Protocatechuic aldehyde protects against experimental sepsis in vitro and in vivo.

Xu, Yong; Jiang, Wang-Lin; Zhang, Shu-Ping; Zhu, Hai-Bo; Hou, Jian

Xu, Yong; Jiang, Wang-Lin; Zhang, Shu-Ping; Zhu, Hai-Bo; Hou, Jian.

Affiliation

Xu Y; School of Pharmaceutical Sciences, Binzhou Medical University, Yantai, China.

Basic Clin Pharmacol Toxicol ; 110(4): 384-9, 2012 Apr.

Article in En | MEDLINE | ID: mdl-22050905

Subject(s)

Benzaldehydes/pharmacology; Catechols/pharmacology; Imipenem/pharmacology; Sepsis/drug therapy; Animals; Anti-Bacterial Agents/administration & dosage; Anti-Bacterial Agents/pharmacology; Benzaldehydes/administration & dosage; Catechols/administration & dosage; Cell Line; Disease Models, Animal; Drug Therapy, Combination; HMGB1 Protein/genetics; Imipenem/administration & dosage; Inflammation/drug therapy; Inflammation/physiopathology; Inflammation Mediators/metabolism; Injections, Intravenous; Interleukin-10/blood; Macrophages/drug effects; Macrophages/metabolism; Male; NF-kappa B/metabolism; Phosphorylation/drug effects; Rats; Rats, Sprague-Dawley; Sepsis/physiopathology; Tumor Necrosis Factor-alpha/administration & dosage

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Benzaldehydes / Catechols / Imipenem / Sepsis Type of study: Prognostic_studies Limits: Animals Language: En Journal: Basic Clin Pharmacol Toxicol Journal subject: FARMACOLOGIA / TOXICOLOGIA Year: 2012 Document type: Article Affiliation country: China Country of publication: United kingdom

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