5-Lipoxygenase-activating protein (FLAP) inhibitors. Part 4: development of 3-[3-tert-butylsulfanyl-1-[4-(6-ethoxypyridin-3-yl)benzyl]-5-(5-methylpyridin-2-ylmethoxy)-1H-indol-2-yl]-2,2-dimethylpropionic acid (AM803), a potent, oral, once daily FLAP inhibitor.
J Med Chem
; 54(23): 8013-29, 2011 Dec 08.
Article
in En
| MEDLINE
| ID: mdl-22059882
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Pentanoic Acids
/
Anti-Asthmatic Agents
/
5-Lipoxygenase-Activating Protein Inhibitors
/
Indoles
Limits:
Animals
/
Female
/
Humans
/
Male
Language:
En
Journal:
J Med Chem
Journal subject:
QUIMICA
Year:
2011
Document type:
Article
Affiliation country:
United States