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Polyaspartic acid coated manganese oxide nanoparticles for efficient liver MRI.
Xing, Ruijun; Zhang, Fan; Xie, Jin; Aronova, Maria; Zhang, Guofeng; Guo, Ning; Huang, Xinglu; Sun, Xiaolian; Liu, Gang; Bryant, L Henry; Bhirde, Ashwinkumar; Liang, Amy; Hou, Yanglong; Leapman, Richard D; Sun, Shouheng; Chen, Xiaoyuan.
Affiliation
  • Xing R; Laboratory of Molecular Imaging and Nanomedicine, National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health, Bethesda, MD 20892, USA.
Nanoscale ; 3(12): 4943-5, 2011 Dec.
Article in En | MEDLINE | ID: mdl-22064945
We report in this communication a simple, facile surface modification strategy to transfer hydrophobic manganese oxide nanoparticles (MONPs) into water by using polyaspartic acid (PASP). We systematically investigated the effect of the size of PASP-MONPs on MRI of normal liver and found that the particles with a core size of 10 nm exhibited greater enhancement than those with larger core sizes.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Peptides / Magnetic Resonance Imaging / Contrast Media / Coated Materials, Biocompatible / Nanoparticles / Liver / Magnesium Oxide Type of study: Diagnostic_studies Limits: Animals Language: En Journal: Nanoscale Year: 2011 Document type: Article Affiliation country: United States Country of publication: United kingdom
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Peptides / Magnetic Resonance Imaging / Contrast Media / Coated Materials, Biocompatible / Nanoparticles / Liver / Magnesium Oxide Type of study: Diagnostic_studies Limits: Animals Language: En Journal: Nanoscale Year: 2011 Document type: Article Affiliation country: United States Country of publication: United kingdom