Cationic liposome-DNA complexes (CLDC) adjuvant enhances the immunogenicity and cross-protective efficacy of a pre-pandemic influenza A H5N1 vaccine in mice.

Dong, Libo; Liu, Feng; Fairman, Jeffery; Hong, David K; Lewis, David B; Monath, Thomas; Warner, John F; Belser, Jessica A; Patel, Jenish; Hancock, Kathy; Katz, Jacqueline M; Lu, Xiuhua

Dong, Libo; Liu, Feng; Fairman, Jeffery; Hong, David K; Lewis, David B; Monath, Thomas; Warner, John F; Belser, Jessica A; Patel, Jenish; Hancock, Kathy; Katz, Jacqueline M; Lu, Xiuhua.

Affiliation

Dong L; Centers for Disease Control and Prevention, Atlanta, GA, USA.

Vaccine ; 30(2): 254-64, 2012 Jan 05.

Article in En | MEDLINE | ID: mdl-22085545

Subject(s)

Adjuvants, Immunologic/administration & dosage; Cations/administration & dosage; DNA/administration & dosage; Drug Carriers/administration & dosage; Influenza A Virus, H5N1 Subtype/immunology; Influenza Vaccines/immunology; Liposomes/administration & dosage; Animals; Antibodies, Viral/blood; CD4-Positive T-Lymphocytes/immunology; Disease Models, Animal; Female; Influenza Vaccines/administration & dosage; Mice; Mice, Inbred BALB C; Orthomyxoviridae Infections/mortality; Orthomyxoviridae Infections/pathology; Orthomyxoviridae Infections/virology; Survival Analysis; Vaccines, Subunit/administration & dosage; Vaccines, Subunit/immunology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: DNA / Drug Carriers / Influenza Vaccines / Cations / Adjuvants, Immunologic / Influenza A Virus, H5N1 Subtype / Liposomes Limits: Animals Language: En Journal: Vaccine Year: 2012 Document type: Article Affiliation country: United States Country of publication: Netherlands

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