Alzheimer Disease/immunology; Alzheimer Disease/pathology; Cognition Disorders/immunology; Interleukin-1beta/antagonists & inhibitors; Neurons/immunology; Signal Transduction/immunology; beta Catenin/physiology; tau Proteins/antagonists & inhibitors; Alzheimer Disease/metabolism; Animals; Cell Line, Tumor; Cells, Cultured; Cognition Disorders/genetics; Cognition Disorders/pathology; Disease Models, Animal; Female; Humans; Interleukin-1beta/physiology; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; NF-kappa B/antagonists & inhibitors; NF-kappa B/metabolism; Nerve Growth Factors/antagonists & inhibitors; Nerve Growth Factors/physiology; Neurons/metabolism; Neurons/pathology; Receptors, Interleukin-1/antagonists & inhibitors; S100 Calcium Binding Protein beta Subunit; S100 Proteins/antagonists & inhibitors; S100 Proteins/physiology; Signal Transduction/genetics; beta Catenin/antagonists & inhibitors; tau Proteins/physiology