Antigens, Neoplasm/physiology; DNA Topoisomerases, Type II/physiology; DNA-Binding Proteins/physiology; Embryonic Development; Zebrafish Proteins/physiology; Zebrafish/embryology; Animals; Antigens, Neoplasm/genetics; Antigens, Neoplasm/metabolism; Base Sequence; Cell Cycle; Cell Extracts; DNA Topoisomerases, Type II/genetics; DNA Topoisomerases, Type II/metabolism; DNA-Binding Proteins/antagonists & inhibitors; DNA-Binding Proteins/genetics; DNA-Binding Proteins/metabolism; Diketopiperazines; Female; Gene Expression; Gene Knockout Techniques; Genes, Recessive; Isoenzymes/genetics; Isoenzymes/metabolism; Isoenzymes/physiology; Male; Phenotype; Phylogeny; Piperazines/pharmacology; Point Mutation; Poly-ADP-Ribose Binding Proteins; Sequence Analysis, DNA; Viviparity, Nonmammalian; Xenopus; Zebrafish Proteins/genetics; Zebrafish Proteins/metabolism; Zygote/metabolism