Aberrant epigenetic regulation of bromodomain BRD4 in human colon cancer.

Rodriguez, R M; Huidobro, C; Urdinguio, R G; Mangas, C; Soldevilla, B; Domínguez, G; Bonilla, F; Fernandez, A F; Fraga, M F

Rodriguez, R M; Huidobro, C; Urdinguio, R G; Mangas, C; Soldevilla, B; Domínguez, G; Bonilla, F; Fernandez, A F; Fraga, M F.

Affiliation

Rodriguez RM; Cancer Epigenetics Laboratory, Instituto Universitario de Oncología del Principado de Asturias (IUOPA), HUCA, Universidad de Oviedo, Oviedo, Spain.

J Mol Med (Berl) ; 90(5): 587-95, 2012 May.

Article in En | MEDLINE | ID: mdl-22120039

Subject(s)

Colonic Neoplasms/genetics; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Nuclear Proteins/genetics; Transcription Factors/genetics; Acetylation; Animals; Cell Cycle Proteins; Cell Line, Tumor; Cell Transformation, Neoplastic/genetics; Cell Transformation, Neoplastic/pathology; DNA Methylation/genetics; Gene Silencing; Histones/metabolism; Humans; Mice; Nuclear Proteins/metabolism; Promoter Regions, Genetic/genetics; Repressor Proteins/genetics; Repressor Proteins/metabolism; Transcription Factors/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Transcription Factors / Nuclear Proteins / Gene Expression Regulation, Neoplastic / Colonic Neoplasms / Epigenesis, Genetic Limits: Animals / Humans Language: En Journal: J Mol Med (Berl) Journal subject: BIOLOGIA MOLECULAR / GENETICA MEDICA Year: 2012 Document type: Article Affiliation country: Spain

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