GraXSR proteins interact with the VraFG ABC transporter to form a five-component system required for cationic antimicrobial peptide sensing and resistance in Staphylococcus aureus.

Falord, Mélanie; Karimova, Gouzel; Hiron, Aurélia; Msadek, Tarek

Falord, Mélanie; Karimova, Gouzel; Hiron, Aurélia; Msadek, Tarek.

Affiliation

Falord M; Institut Pasteur, Biology of Gram-Positive Pathogens, Department of Microbiology, Paris, France.

Antimicrob Agents Chemother ; 56(2): 1047-58, 2012 Feb.

Article in En | MEDLINE | ID: mdl-22123691

Subject(s)

Antimicrobial Cationic Peptides/pharmacology; Bacterial Proteins/metabolism; Drug Resistance, Bacterial/genetics; Gene Expression Regulation, Bacterial; Signal Transduction; Staphylococcus aureus/drug effects; ATP-Binding Cassette Transporters/genetics; ATP-Binding Cassette Transporters/metabolism; Anti-Bacterial Agents/pharmacology; Bacterial Proteins/genetics; Histidine Kinase; Humans; Membrane Transport Proteins/genetics; Membrane Transport Proteins/metabolism; Microbial Sensitivity Tests; Mutagenesis, Site-Directed; Plasmids; Protein Kinases/genetics; Protein Kinases/metabolism; Staphylococcus aureus/genetics; Staphylococcus aureus/metabolism

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Staphylococcus aureus / Bacterial Proteins / Signal Transduction / Gene Expression Regulation, Bacterial / Antimicrobial Cationic Peptides / Drug Resistance, Bacterial Limits: Humans Language: En Journal: Antimicrob Agents Chemother Year: 2012 Document type: Article Affiliation country: France Country of publication: United States

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google