Optimization of mass spectrometers using the adaptive particle swarm algorithm.
J Mass Spectrom
; 46(11): 1143-51, 2011 Nov.
Article
in En
| MEDLINE
| ID: mdl-22124986
ABSTRACT
Optimization of mass spectrometers using the adaptive particle swarm algorithm (APSA) is described along with implementations for ion optical simulations and various time-of-flight (TOF) instruments. The need for in situ self optimization is addressed through discussion of the reflectron TOF mass spectrometer (RTOF) on the European Space Agency mission Rosetta. In addition, a tool for optimization of laboratory mass spectrometers is presented and tested on two different instruments. After the application of APSA optimization, a substantial increase in performance for mass spectrometers that have manually been tuned for several weeks or months is demonstrated.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Type of study:
Prognostic_studies
Language:
En
Journal:
J Mass Spectrom
Journal subject:
BIOQUIMICA
Year:
2011
Document type:
Article
Affiliation country:
Switzerland
Publication country:
ENGLAND
/
ESCOCIA
/
GB
/
GREAT BRITAIN
/
INGLATERRA
/
REINO UNIDO
/
SCOTLAND
/
UK
/
UNITED KINGDOM