Association of cartilage-specific deletion of peroxisome proliferator-activated receptor Î³ with abnormal endochondral ossification and impaired cartilage growth and development in a murine model.

Monemdjou, Roxana; Vasheghani, Faezeh; Fahmi, Hassan; Perez, Gemma; Blati, Meryem; Taniguchi, Noboru; Lotz, Martin; St-Arnaud, René; Pelletier, Jean-Pierre; Martel-Pelletier, Johanne; Beier, Frank; Kapoor, Mohit

Monemdjou, Roxana; Vasheghani, Faezeh; Fahmi, Hassan; Perez, Gemma; Blati, Meryem; Taniguchi, Noboru; Lotz, Martin; St-Arnaud, René; Pelletier, Jean-Pierre; Martel-Pelletier, Johanne; Beier, Frank; Kapoor, Mohit.

Affiliation

Monemdjou R; University of Montreal Hospital Research Centre and University of Montreal, Montreal, Quebec, Canada.

Arthritis Rheum ; 64(5): 1551-61, 2012 May.

Article in En | MEDLINE | ID: mdl-22131019

Subject(s)

Bone and Bones/pathology; Cartilage/pathology; Chondrocytes/metabolism; Chondrogenesis/physiology; Osteogenesis/physiology; PPAR gamma/biosynthesis; Animals; Biomarkers/metabolism; Bone Density; Bone Development; Bone and Bones/metabolism; Cartilage/growth & development; Cartilage/metabolism; Cell Differentiation; Cell Proliferation; Cells, Cultured; Disease Models, Animal; Hedgehog Proteins/metabolism; Hypertrophy; Mice; Mice, Inbred C57BL; Mice, Knockout; PPAR gamma/deficiency; PPAR gamma/genetics; Phosphorylation; p38 Mitogen-Activated Protein Kinases/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Osteogenesis / Bone and Bones / Cartilage / Chondrocytes / Chondrogenesis / PPAR gamma Type of study: Prognostic_studies / Risk_factors_studies Limits: Animals Language: En Journal: Arthritis Rheum Year: 2012 Document type: Article Affiliation country: Canada

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