Congenital CNS hypomyelination in the Fig4 null mouse is rescued by neuronal expression of the PI(3,5)P(2) phosphatase Fig4.

Winters, Jesse J; Ferguson, Cole J; Lenk, Guy M; Giger-Mateeva, Vessela I; Shrager, Peter; Meisler, Miriam H; Giger, Roman J

Winters, Jesse J; Ferguson, Cole J; Lenk, Guy M; Giger-Mateeva, Vessela I; Shrager, Peter; Meisler, Miriam H; Giger, Roman J.

Affiliation

Winters JJ; Department of Cell and Developmental Biology, University of Michigan, Ann Arbor, Michigan 48109-2200, USA.

J Neurosci ; 31(48): 17736-51, 2011 Nov 30.

Article in En | MEDLINE | ID: mdl-22131434

Subject(s)

Axons/pathology; Charcot-Marie-Tooth Disease/genetics; Flavoproteins/genetics; Myelin Sheath/genetics; Nerve Fibers, Myelinated/pathology; Neurons/metabolism; Phosphoric Monoester Hydrolases/genetics; Animals; Axons/metabolism; Charcot-Marie-Tooth Disease/metabolism; Charcot-Marie-Tooth Disease/pathology; Flavoproteins/metabolism; Mice; Mice, Transgenic; Myelin Sheath/metabolism; Myelin Sheath/pathology; Nerve Fibers, Myelinated/metabolism; Neurons/pathology; Phosphatidylinositols/metabolism; Phosphoinositide Phosphatases; Phosphoric Monoester Hydrolases/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Axons / Charcot-Marie-Tooth Disease / Phosphoric Monoester Hydrolases / Flavoproteins / Myelin Sheath / Nerve Fibers, Myelinated / Neurons Limits: Animals Language: En Journal: J Neurosci Year: 2011 Document type: Article Affiliation country: United States Country of publication: United States

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