The influence of methotrexate on the gene expression of the pro-inflammatory cytokine IL-12A in the therapy of rheumatoid arthritis.

Hobl, Eva-Luise; Mader, Robert M; Erlacher, Ludwig; Duhm, Bernhard; Mustak, Monika; Bröll, Hans; Högger, Petra; Kalipciyan, Maria; Jilma, Bernd

Hobl, Eva-Luise; Mader, Robert M; Erlacher, Ludwig; Duhm, Bernhard; Mustak, Monika; Bröll, Hans; Högger, Petra; Kalipciyan, Maria; Jilma, Bernd.

Affiliation

Hobl EL; Medical University of Vienna, Department of Clinical Pharmacology, Vienna, Austria. eva-luise.hobl@meduniwien.ac.at

Clin Exp Rheumatol ; 29(6): 963-9, 2011.

Article in En | MEDLINE | ID: mdl-22133036

Subject(s)

Antirheumatic Agents/therapeutic use; Arthritis, Rheumatoid/drug therapy; Gene Expression/drug effects; Interleukin-12 Subunit p35/genetics; Methotrexate/therapeutic use; Anti-Inflammatory Agents, Non-Steroidal/therapeutic use; Antirheumatic Agents/pharmacokinetics; Arthritis, Rheumatoid/genetics; Arthritis, Rheumatoid/physiopathology; Double-Blind Method; Drug Therapy, Combination; Female; Glucocorticoids/therapeutic use; Health Status; Humans; Interleukin-12 Subunit p35/metabolism; Interleukin-18/genetics; Interleukin-18/metabolism; Leukocytes, Mononuclear/drug effects; Leukocytes, Mononuclear/metabolism; Male; Methotrexate/analogs & derivatives; Methotrexate/blood; Methotrexate/pharmacokinetics; Middle Aged; Polyglutamic Acid/analogs & derivatives; Polyglutamic Acid/blood; RNA, Messenger/metabolism; Severity of Illness Index; Treatment Outcome

Search on Google

Add to My VHL

XML

PubMed Links

Collection: 01-internacional Database: MEDLINE Main subject: Arthritis, Rheumatoid / Gene Expression / Methotrexate / Antirheumatic Agents / Interleukin-12 Subunit p35 Type of study: Clinical_trials Aspects: Patient_preference Limits: Female / Humans / Male / Middle aged Language: En Journal: Clin Exp Rheumatol Year: 2011 Document type: Article Affiliation country: Austria Country of publication: Italy

Search on Google

Add to My VHL

XML

PubMed Links