miR-15a and miR-16-1 inhibit the proliferation of leukemic cells by down-regulating WT1 protein level.

Gao, Shen-meng; Xing, Chong-yun; Chen, Chi-qi; Lin, Si-si; Dong, Pei-hong; Yu, Fu-jun

Gao, Shen-meng; Xing, Chong-yun; Chen, Chi-qi; Lin, Si-si; Dong, Pei-hong; Yu, Fu-jun.

Affiliation

Gao SM; Laboratory of Internal Medicine, The First Affiliated Hospital of Wenzhou Medical College, China.

J Exp Clin Cancer Res ; 30: 110, 2011 Dec 01.

Article in En | MEDLINE | ID: mdl-22133358

Subject(s)

Down-Regulation; Leukemia/genetics; Leukemia/metabolism; MicroRNAs/metabolism; WT1 Proteins/metabolism; 3' Untranslated Regions; Cell Line, Tumor; Cell Proliferation; Gene Expression Regulation, Neoplastic; HL-60 Cells; Humans; K562 Cells; Oligonucleotides, Antisense; RNA, Messenger/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Leukemia / Down-Regulation / WT1 Proteins / MicroRNAs Limits: Humans Language: En Journal: J Exp Clin Cancer Res Year: 2011 Document type: Article Affiliation country: China

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