Controlled release of a highly hydrophilic API from lipid microspheres obtained by prilling: analysis of drug and water diffusion processes with X-ray-based methods.

Pivette, Perrine; Faivre, Vincent; Mancini, Lucia; Gueutin, Claire; Daste, Georges; Ollivon, Michel; Lesieur, Sylviane

Pivette, Perrine; Faivre, Vincent; Mancini, Lucia; Gueutin, Claire; Daste, Georges; Ollivon, Michel; Lesieur, Sylviane.

Affiliation

Pivette P; Université Paris-Sud XI, UMR CNRS 8612, 5 rue JB Clément, 92290 Châtenay Malabry, France.

J Control Release ; 158(3): 393-402, 2012 Mar 28.

Article in En | MEDLINE | ID: mdl-22138071

Subject(s)

Delayed-Action Preparations/chemistry; Drug Compounding/methods; Microspheres; Anticonvulsants/chemistry; Diffusion; Excipients/chemistry; Fatty Acids/chemistry; Hydrophobic and Hydrophilic Interactions; Paraffin/chemistry; Valproic Acid/chemistry; Water/chemistry; X-Ray Diffraction

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Delayed-Action Preparations / Drug Compounding / Microspheres Type of study: Prognostic_studies Language: En Journal: J Control Release Journal subject: FARMACOLOGIA Year: 2012 Document type: Article Affiliation country: France

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