The molecular basis of acid insensitivity in the African naked mole-rat.

Smith, Ewan St John; Omerbasic, Damir; Lechner, Stefan G; Anirudhan, Gireesh; Lapatsina, Liudmila; Lewin, Gary R

The molecular basis of acid insensitivity in the African naked mole-rat.

Smith, Ewan St John; Omerbasic, Damir; Lechner, Stefan G; Anirudhan, Gireesh; Lapatsina, Liudmila; Lewin, Gary R.

Affiliation

Smith ES; Department of Neuroscience, Max-Delbrück Center for Molecular Medicine, Berlin-Buch, Germany. ewan.smith@mdc-berlin.de

Science ; 334(6062): 1557-60, 2011 Dec 16.

Article in En | MEDLINE | ID: mdl-22174253

Subject(s)

Acids/pharmacology; Mole Rats/physiology; Nociception/physiology; Sodium Channels/metabolism; Acid Sensing Ion Channels; Acids/metabolism; Action Potentials; Amino Acid Motifs; Animals; Ganglia, Spinal/cytology; Ganglia, Spinal/physiology; Mice; Mole Rats/genetics; NAV1.7 Voltage-Gated Sodium Channel; Nerve Tissue Proteins/metabolism; Rats; Sodium Channels/genetics; TRPV Cation Channels/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Acids / Sodium Channels / Mole Rats / Nociception Limits: Animals Language: En Journal: Science Year: 2011 Document type: Article Affiliation country: Germany Country of publication: United States

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