Synthesis of a covalent epirubicin-(C(3)-amide)-anti-HER2/neu immunochemotherapeutic utilizing a UV-photoactivated anthracycline intermediate.

Coyne, Cody P; Jones, Toni; Bear, Ryan

Coyne, Cody P; Jones, Toni; Bear, Ryan.

Affiliation

Coyne CP; Department of Basic Sciences, College of Veterinary Medicine, Mississippi State University, Mississippi State, Mississippi, USA. coyne@cvm.msstate.edu

Cancer Biother Radiopharm ; 27(1): 41-55, 2012 Feb.

Article in En | MEDLINE | ID: mdl-22191802

Subject(s)

Antibiotics, Antineoplastic/chemical synthesis; Breast Neoplasms/drug therapy; Epirubicin/analogs & derivatives; Receptor, ErbB-2/antagonists & inhibitors; Adenocarcinoma/drug therapy; Adenocarcinoma/enzymology; Adenocarcinoma/genetics; Adenocarcinoma/pathology; Antibiotics, Antineoplastic/chemistry; Antibiotics, Antineoplastic/pharmacology; Breast Neoplasms/enzymology; Breast Neoplasms/immunology; Breast Neoplasms/pathology; Cell Line, Tumor; Enzyme-Linked Immunosorbent Assay; Epirubicin/chemical synthesis; Epirubicin/pharmacology; Female; Humans; Immunoglobulin G/immunology; Photochemical Processes; Tumor Cells, Cultured; Ultraviolet Rays

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Breast Neoplasms / Epirubicin / Receptor, ErbB-2 / Antibiotics, Antineoplastic Limits: Female / Humans Language: En Journal: Cancer Biother Radiopharm Journal subject: FARMACIA / FARMACOLOGIA / NEOPLASIAS / TERAPEUTICA Year: 2012 Document type: Article Affiliation country: United States Country of publication: United States

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