Development and validation of a sensitive solid-phase-extraction (SPE) method using high-performance liquid chromatography/tandem mass spectrometry (LC-MS/MS) for determination of risedronate concentrations in human plasma.

Ghassabian, Sussan; Wright, Linda A; Dejager, Andrew D; Smith, Maree T

Ghassabian, Sussan; Wright, Linda A; Dejager, Andrew D; Smith, Maree T.

Affiliation

Ghassabian S; Centre for Integrated Preclinical Drug Development, The University of Queensland, Brisbane, QLD, Australia. s.ghassabian@uq.edu.au

J Chromatogr B Analyt Technol Biomed Life Sci ; 881-882: 34-41, 2012 Jan 15.

Article in En | MEDLINE | ID: mdl-22197608

Subject(s)

Chromatography, High Pressure Liquid/methods; Etidronic Acid/analogs & derivatives; Solid Phase Extraction/methods; Tandem Mass Spectrometry/methods; Acetaminophen/blood; Acetaminophen/isolation & purification; Diazomethane/analogs & derivatives; Drug Stability; Etidronic Acid/blood; Etidronic Acid/chemistry; Etidronic Acid/pharmacokinetics; Hemolysis; Humans; Ibuprofen/blood; Ibuprofen/isolation & purification; Regression Analysis; Reproducibility of Results; Risedronic Acid; Sensitivity and Specificity; Trimethylsilyl Compounds

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Chromatography, High Pressure Liquid / Etidronic Acid / Tandem Mass Spectrometry / Solid Phase Extraction Type of study: Diagnostic_studies / Guideline Limits: Humans Language: En Journal: J Chromatogr B Analyt Technol Biomed Life Sci Journal subject: ENGENHARIA BIOMEDICA Year: 2012 Document type: Article Affiliation country: Australia Country of publication: Netherlands

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