Activation of the central melanocortin system contributes to the increased arterial pressure in obese Zucker rats.

do Carmo, Jussara M; da Silva, Alexandre A; Rushing, John S; Hall, John E

do Carmo, Jussara M; da Silva, Alexandre A; Rushing, John S; Hall, John E.

Affiliation

do Carmo JM; Department of Physiology and Biophysics, University of Mississippi Medical Center, Jackson, MS 39216-4505, USA. jdocarmo@umc.edu

Am J Physiol Regul Integr Comp Physiol ; 302(5): R561-7, 2012 Mar 01.

Article in En | MEDLINE | ID: mdl-22204957

Subject(s)

Blood Pressure/physiology; Central Nervous System/physiology; Hypertension/physiopathology; Melanocortins/physiology; Obesity/physiopathology; Animals; Blood Glucose/metabolism; Disease Models, Animal; Heart Rate/physiology; Infusions, Intraventricular; Insulin/blood; Male; Melanocyte-Stimulating Hormones/administration & dosage; Melanocyte-Stimulating Hormones/pharmacology; Obesity/blood; Rats; Rats, Zucker; Receptor, Melanocortin, Type 3/antagonists & inhibitors; Receptor, Melanocortin, Type 3/drug effects; Receptor, Melanocortin, Type 4/antagonists & inhibitors; Receptor, Melanocortin, Type 4/drug effects; Receptors, Leptin/physiology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Blood Pressure / Central Nervous System / Melanocortins / Hypertension / Obesity Limits: Animals Language: En Journal: Am J Physiol Regul Integr Comp Physiol Journal subject: FISIOLOGIA Year: 2012 Document type: Article Affiliation country: United States Country of publication: United States

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