Inhaled neutrophil elastase inhibitor reduces oleic acid-induced acute lung injury in rats.

Tao, Wei; Miao, Qian-Bing; Zhu, Ya-Bing; Shu, Yu-Sheng

Tao, Wei; Miao, Qian-Bing; Zhu, Ya-Bing; Shu, Yu-Sheng.

Affiliation

Tao W; Department of Thoracic Surgery, Subei People's Hospital of Jiangsu province, Yangzhou 225001, Jiangsu, PR China.

Pulm Pharmacol Ther ; 25(1): 99-103, 2012 Feb.

Article in En | MEDLINE | ID: mdl-22210005

Subject(s)

Acute Lung Injury/chemically induced; Acute Lung Injury/drug therapy; Glycine/analogs & derivatives; Leukocyte Elastase/antagonists & inhibitors; Oleic Acid; Proteinase Inhibitory Proteins, Secretory/pharmacology; Sulfonamides/pharmacology; Acute Lung Injury/enzymology; Administration, Inhalation; Albumins/analysis; Albumins/metabolism; Animals; Blood Gas Analysis; Bronchoalveolar Lavage Fluid/chemistry; Bronchoalveolar Lavage Fluid/cytology; Cell Count; Extravascular Lung Water/drug effects; Female; Glycine/administration & dosage; Glycine/pharmacology; Injections, Intravenous; Leukocyte Count; Leukocyte Elastase/metabolism; Ovalbumin/administration & dosage; Ovalbumin/toxicity; Peroxidase/metabolism; Proteinase Inhibitory Proteins, Secretory/administration & dosage; Rats; Rats, Sprague-Dawley; Serum Albumin, Bovine/administration & dosage; Serum Albumin, Bovine/toxicity; Sulfonamides/administration & dosage; Survival Analysis

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Sulfonamides / Oleic Acid / Leukocyte Elastase / Proteinase Inhibitory Proteins, Secretory / Acute Lung Injury / Glycine Limits: Animals Language: En Journal: Pulm Pharmacol Ther Journal subject: FARMACOLOGIA Year: 2012 Document type: Article

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google