Elevated interleukin-27 enhances the polarization of Th1/Tc1 cells and the production of proinflammatory cytokines in primary immune thrombocytopenia.

Li, Hui Yuan; Zhang, Dong Lei; Ge, Jing; Zhou, Hu; Qi, Ai ping; Ma, Li; Xue, Feng; Zhou, Ze Ping; Yang, Ren Chi

Li, Hui Yuan; Zhang, Dong Lei; Ge, Jing; Zhou, Hu; Qi, Ai ping; Ma, Li; Xue, Feng; Zhou, Ze Ping; Yang, Ren Chi.

Affiliation

Li HY; State Key Laboratory of Experimental Hematology, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin 300020, People's Republic of China.

Hum Immunol ; 73(3): 240-7, 2012 Mar.

Article in En | MEDLINE | ID: mdl-22210084

Subject(s)

Interleukins/metabolism; Purpura, Thrombocytopenic, Idiopathic/immunology; T-Lymphocytes/metabolism; Adolescent; Adult; Aged; Aged, 80 and over; Cells, Cultured; Cytokines/genetics; Cytokines/metabolism; Female; Gene Expression Regulation/immunology; Humans; Inflammation Mediators/metabolism; Interleukins/genetics; Interleukins/immunology; Male; Middle Aged; Receptors, Interleukin/genetics; Receptors, Interleukin/metabolism; T-Lymphocytes/immunology; T-Lymphocytes/pathology; Th1-Th2 Balance; Transcription Factors/genetics; Transcription Factors/metabolism; Young Adult

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: T-Lymphocytes / Interleukins / Purpura, Thrombocytopenic, Idiopathic Limits: Adolescent / Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Language: En Journal: Hum Immunol Year: 2012 Document type: Article Country of publication: United States

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