Population pharmacokinetics of cytarabine, etoposide, and daunorubicin in the treatment for acute myeloid leukemia.

Krogh-Madsen, Mikkel; Bender, Brendan; Jensen, Morten Krogh; Nielsen, Ove Juul; Friberg, Lena E; Honoré, Per Hartvig

Krogh-Madsen, Mikkel; Bender, Brendan; Jensen, Morten Krogh; Nielsen, Ove Juul; Friberg, Lena E; Honoré, Per Hartvig.

Affiliation

Krogh-Madsen M; Department of Pharmacology and Pharmacotherapy, Faculty of Pharmaceutical Sciences, University of Copenhagen, Jagtvej 160, 2100 Copenhagen, Denmark. mkm@farma.ku.dk

Cancer Chemother Pharmacol ; 69(5): 1155-63, 2012 May.

Article in En | MEDLINE | ID: mdl-22212298

Subject(s)

Antineoplastic Combined Chemotherapy Protocols/pharmacokinetics; Leukemia, Myeloid, Acute/drug therapy; Models, Biological; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols/administration & dosage; Antineoplastic Combined Chemotherapy Protocols/therapeutic use; Body Surface Area; Chromatography, High Pressure Liquid; Creatinine/blood; Creatinine/urine; Cytarabine/administration & dosage; Daunorubicin/administration & dosage; Dose-Response Relationship, Drug; Etoposide/administration & dosage; Female; Humans; Leukemia, Myeloid, Acute/pathology; Leukocyte Count; Male; Middle Aged; Nonlinear Dynamics; Prospective Studies; Tissue Distribution; Young Adult

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Leukemia, Myeloid, Acute / Antineoplastic Combined Chemotherapy Protocols / Models, Biological Type of study: Observational_studies / Risk_factors_studies Limits: Adult / Aged / Female / Humans / Male / Middle aged Language: En Journal: Cancer Chemother Pharmacol Year: 2012 Document type: Article Affiliation country: Denmark

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