The NLRP3/ASC/Caspase-1 axis regulates IL-1ß processing in neutrophils.

Mankan, Arun K; Dau, Therese; Jenne, Dieter; Hornung, Veit

Mankan, Arun K; Dau, Therese; Jenne, Dieter; Hornung, Veit.

Affiliation

Mankan AK; Institute for Clinical Chemistry and Clinical Pharmacology, Unit for Clinical Biochemistry, University Hospital, University of Bonn, Bonn, Germany.

Eur J Immunol ; 42(3): 710-5, 2012 Mar.

Article in En | MEDLINE | ID: mdl-22213227

Subject(s)

Carrier Proteins/immunology; Caspase 1/immunology; Cytoskeletal Proteins/immunology; Interleukin-1beta/immunology; Neutrophils/immunology; Animals; Apoptosis Regulatory Proteins; CARD Signaling Adaptor Proteins; Flow Cytometry; Immunity, Innate/immunology; Inflammasomes/immunology; Interleukin-1beta/genetics; Macrophages, Peritoneal/immunology; Mice; Mice, Inbred C57BL; Mice, Knockout; NLR Family, Pyrin Domain-Containing 3 Protein; RNA/chemistry; RNA/genetics; Real-Time Polymerase Chain Reaction

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Carrier Proteins / Caspase 1 / Cytoskeletal Proteins / Interleukin-1beta / Neutrophils Type of study: Prognostic_studies Limits: Animals Language: En Journal: Eur J Immunol Year: 2012 Document type: Article Affiliation country: Germany

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