Involvement of specific transport system on uptake of lactone form of SN-38 in human intestinal epithelial cell line Caco-2.

Ueno, Yusuke; Matsuda, Hiroko; Mizutani, Hideki; Iwamoto, Takuya; Okuda, Masahiro

Ueno, Yusuke; Matsuda, Hiroko; Mizutani, Hideki; Iwamoto, Takuya; Okuda, Masahiro.

Affiliation

Ueno Y; Department of Clinical Pharmacy and Biopharmaceutics, Graduate School of Medicine, Mie University, Edobashi, Tsu, Mie 5148507, Japan.

Biol Pharm Bull ; 35(1): 54-8, 2012.

Article in En | MEDLINE | ID: mdl-22223337

Subject(s)

Camptotheca/chemistry; Camptothecin/analogs & derivatives; Epithelial Cells/metabolism; Intestinal Mucosa/metabolism; Lactones/metabolism; Biological Transport; Caco-2 Cells; Camptothecin/metabolism; Camptothecin/pharmacology; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal/chemistry; Drugs, Chinese Herbal/pharmacology; Estrone/pharmacology; Flavonoids/pharmacology; Humans; Intestinal Absorption; Irinotecan; Sulfobromophthalein/pharmacology; Taurocholic Acid/pharmacology

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Collection: 01-internacional Database: MEDLINE Main subject: Camptothecin / Camptotheca / Epithelial Cells / Intestinal Mucosa / Lactones Limits: Humans Language: En Journal: Biol Pharm Bull Journal subject: BIOQUIMICA / FARMACOLOGIA Year: 2012 Document type: Article Affiliation country: Japan Country of publication: Japan

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