Population pharmacokinetics of rituximab in patients with chronic lymphocytic leukemia.

Li, Jing; Zhi, Jianguo; Wenger, Michael; Valente, Nancy; Dmoszynska, Anna; Robak, Tadeusz; Mangat, Ranvir; Joshi, Amita; Visich, Jennifer

Li, Jing; Zhi, Jianguo; Wenger, Michael; Valente, Nancy; Dmoszynska, Anna; Robak, Tadeusz; Mangat, Ranvir; Joshi, Amita; Visich, Jennifer.

Affiliation

Li J; Clinical Pharmacology, MS 463a, Genentech Inc, 1 DNA Way, South San Francisco, CA 94080, USA. li.jing@gene.com

J Clin Pharmacol ; 52(12): 1918-26, 2012 Dec.

Article in En | MEDLINE | ID: mdl-22235140

Subject(s)

Antineoplastic Combined Chemotherapy Protocols/pharmacokinetics; Leukemia, Lymphocytic, Chronic, B-Cell/metabolism; Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal, Murine-Derived/administration & dosage; Antineoplastic Agents/administration & dosage; Antineoplastic Agents/blood; Antineoplastic Combined Chemotherapy Protocols/administration & dosage; Antineoplastic Combined Chemotherapy Protocols/blood; Computer Simulation; Cyclophosphamide/administration & dosage; Drug Interactions; Female; Humans; Leukemia, Lymphocytic, Chronic, B-Cell/drug therapy; Male; Middle Aged; Models, Biological; Retrospective Studies; Rituximab; Vidarabine/administration & dosage; Vidarabine/analogs & derivatives

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Leukemia, Lymphocytic, Chronic, B-Cell / Antineoplastic Combined Chemotherapy Protocols Type of study: Observational_studies / Risk_factors_studies Limits: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Language: En Journal: J Clin Pharmacol Year: 2012 Document type: Article Affiliation country: United States Country of publication: United kingdom

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