&#916;-lactam derivative from thermophilic soil fungus exhibits in vitro anti-allergic activity.

Andrioli, W J; Santos, M S; Silva, V B; Oliveira, R B; Chagas-Paula, D A; Jorge, J A; Furtado, N A J C; Pupo, M T; Silva, C H T P; Naal, R M Z G; Bastos, J K

Δ-lactam derivative from thermophilic soil fungus exhibits in vitro anti-allergic activity.

Andrioli, W J; Santos, M S; Silva, V B; Oliveira, R B; Chagas-Paula, D A; Jorge, J A; Furtado, N A J C; Pupo, M T; Silva, C H T P; Naal, R M Z G; Bastos, J K.

Affiliation

Andrioli WJ; Departamento de Ciências Farmacêuticas, Universidade de São Paulo, Avenida do Café, s/n, CEP 14040-903, Ribeirão Preto, São Paulo, Brasil.

Nat Prod Res ; 26(23): 2168-75, 2012.

Article in En | MEDLINE | ID: mdl-22239222

Subject(s)

Anti-Allergic Agents/chemistry; Anti-Allergic Agents/pharmacology; Ascomycota/chemistry; Lactams/chemistry; Pyridones/chemistry; Pyridones/pharmacology; Animals; Cell Degranulation/drug effects; Cell Line, Tumor; Cell Survival/drug effects; Computer Simulation; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical/methods; Inhibitory Concentration 50; Ketotifen/pharmacology; Magnetic Resonance Spectroscopy; Molecular Structure; Phthalazines/pharmacology; Rats; Soil Microbiology; beta-N-Acetylhexosaminidases/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Ascomycota / Pyridones / Anti-Allergic Agents / Lactams Type of study: Prognostic_studies Limits: Animals Language: En Journal: Nat Prod Res Year: 2012 Document type: Article Affiliation country: Brazil

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