Simvastatin modulates remodeling of Kv4.3 expression in rat hypertrophied cardiomyocytes.

Su, Feifei; Shi, Miaoqian; Yan, Zhiqiang; Ou, Dongbo; Li, Juntang; Lu, Zifan; Zheng, Qiangsun

Su, Feifei; Shi, Miaoqian; Yan, Zhiqiang; Ou, Dongbo; Li, Juntang; Lu, Zifan; Zheng, Qiangsun.

Affiliation

Su F; Department of Cardiology, Tangdu Hospital, Fourth Military Medical University, Xi'an, China. sufeifei@fmmu.edu.cn

Int J Biol Sci ; 8(2): 236-48, 2012.

Article in En | MEDLINE | ID: mdl-22253567

Subject(s)

Gene Expression Regulation/drug effects; Hydroxymethylglutaryl-CoA Reductase Inhibitors/pharmacology; Myocytes, Cardiac/drug effects; Shal Potassium Channels/metabolism; Simvastatin/pharmacology; Animals; Calcineurin/metabolism; Cardiomegaly/drug therapy; Cardiomegaly/pathology; Lipid Metabolism/drug effects; Male; Myocytes, Cardiac/metabolism; Rats; Rats, Sprague-Dawley; Shal Potassium Channels/genetics

Key words

Kv4.3; Potassium channels; arrhythmias; hydroxymethylglutaryl-CoA reductase inhibitors; hypertrophy.

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Gene Expression Regulation / Hydroxymethylglutaryl-CoA Reductase Inhibitors / Simvastatin / Myocytes, Cardiac / Shal Potassium Channels Limits: Animals Language: En Journal: Int J Biol Sci Journal subject: BIOLOGIA Year: 2012 Document type: Article Affiliation country: China Country of publication: Australia

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