Effect of functional status on survival in patients with stroke: is independent ambulation a key determinant?
Arch Phys Med Rehabil
; 93(3): 527-31, 2012 Mar.
Article
in En
| MEDLINE
| ID: mdl-22265084
ABSTRACT
OBJECTIVE:
To investigate the effect of functional status, measured using the Modified Rankin Scale (MRS), at 3 months after stroke on survival in patients with stroke.DESIGN:
Cohort study.SETTING:
Referral medical center.PARTICIPANTS:
Patients with stroke (N=1032).INTERVENTIONS:
Not applicable. MAIN OUTCOMEMEASURE:
Survival after stroke.RESULTS:
The Kaplan-Meier survival curves stratified by the 3-month MRS score showed 2 clear groups of patients with 3-month MRS scores of 0 to 3 (able to walk without assistance) and 4 or 5 (unable to walk without assistance). Accordingly, we grouped the patients into a high function (HF) group (3-month MRSâ¦3) and a low function (LF) group (3-month MRSâ§4). Multiple Cox regression analysis showed that the LF group had significantly poorer survival (adjusted hazard ratio=4.69; 95% confidence interval [CI], 2.89-7.60; P<.001) than the HF group. Other significant risk factors of higher mortality were older age, history of diabetes mellitus, and heart disease.CONCLUSIONS:
This study showed a significant influence of the 3-month MRS score on stroke survival. Moreover, independent ambulation may be a major determinant of a favorable survival prognosis. This finding suggests a potential role of rehabilitation in promoting stroke survival by maximizing ambulation function.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Survival
/
Activities of Daily Living
/
Stroke
/
Stroke Rehabilitation
/
Motor Activity
Type of study:
Etiology_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limits:
Adult
/
Aged
/
Aged80
/
Female
/
Humans
/
Male
/
Middle aged
Language:
En
Journal:
Arch Phys Med Rehabil
Year:
2012
Document type:
Article
Affiliation country:
Taiwan