P-selectin-mediated platelet activation promotes adhesion of non-small             cell lung carcinoma cells on vascular endothelial cells under flow.

Gong, Liang; Mi, Hong-Jian; Zhu, Hongchu; Zhou, Xiangdong; Yang, Heping

P-selectin-mediated platelet activation promotes adhesion of non-small cell lung carcinoma cells on vascular endothelial cells under flow.

Gong, Liang; Mi, Hong-Jian; Zhu, Hongchu; Zhou, Xiangdong; Yang, Heping.

Affiliation

Gong L; Department of Respiration, The Southwest Hospital, The Third Military Medical University, Chongqing 400038, PR China.

Mol Med Rep ; 5(4): 935-42, 2012 Apr.

Article in En | MEDLINE | ID: mdl-22266541

Subject(s)

Blood Platelets/drug effects; Cell Adhesion/drug effects; P-Selectin/pharmacology; Blood Platelets/metabolism; Carcinoma, Non-Small-Cell Lung/metabolism; Carcinoma, Non-Small-Cell Lung/pathology; Cells, Cultured; Coculture Techniques; Human Umbilical Vein Endothelial Cells/cytology; Humans; Integrin alpha3/genetics; Integrin alpha3/metabolism; Integrin alpha5/genetics; Integrin alpha5/metabolism; Integrin beta1/genetics; Integrin beta1/metabolism; Intercellular Adhesion Molecule-1/genetics; Intercellular Adhesion Molecule-1/metabolism; Lung Neoplasms/metabolism; Lung Neoplasms/pathology; Membrane Glycoproteins/antagonists & inhibitors; Membrane Glycoproteins/genetics; Membrane Glycoproteins/metabolism; Platelet Activation; RNA Interference; RNA, Small Interfering/metabolism; Vascular Cell Adhesion Molecule-1/genetics; Vascular Cell Adhesion Molecule-1/metabolism

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Blood Platelets / Cell Adhesion / P-Selectin Limits: Humans Language: En Journal: Mol Med Rep Year: 2012 Document type: Article Country of publication: Greece

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google