RhoA triggers a specific signaling pathway that generates transforming microvesicles in cancer cells.

Li, B; Antonyak, M A; Zhang, J; Cerione, R A

Li, B; Antonyak, M A; Zhang, J; Cerione, R A.

Affiliation

Li B; Department of Molecular Medicine, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853-6401, USA.

Oncogene ; 31(45): 4740-9, 2012 Nov 08.

Article in En | MEDLINE | ID: mdl-22266864

Subject(s)

Cell Transformation, Neoplastic/metabolism; Cell-Derived Microparticles/metabolism; Neoplasms/metabolism; Signal Transduction; rhoA GTP-Binding Protein/metabolism; Actin Depolymerizing Factors/metabolism; Animals; Cell Line, Tumor; Enzyme Activation; Humans; Lim Kinases/metabolism; Mice; rho-Associated Kinases/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Signal Transduction / Cell Transformation, Neoplastic / RhoA GTP-Binding Protein / Cell-Derived Microparticles / Neoplasms Limits: Animals / Humans Language: En Journal: Oncogene Journal subject: BIOLOGIA MOLECULAR / NEOPLASIAS Year: 2012 Document type: Article Affiliation country: United States Country of publication: United kingdom

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