&#945;7 neuronal nicotinic receptor agonist (TC-7020) reverses increased striatal dopamine release during acoustic PPI testing in a transgenic mouse model of schizophrenia.

Kucinski, A; Syposs, C; Wersinger, S; Bencherif, M; Stachowiak, M K; Stachowiak, E K

α7 neuronal nicotinic receptor agonist (TC-7020) reverses increased striatal dopamine release during acoustic PPI testing in a transgenic mouse model of schizophrenia.

Kucinski, A; Syposs, C; Wersinger, S; Bencherif, M; Stachowiak, M K; Stachowiak, E K.

Affiliation

Kucinski A; Department of Pathology and Anatomical Sciences, SUNY, Buffalo, NY 14214, USA.

Schizophr Res ; 136(1-3): 82-7, 2012 Apr.

Article in En | MEDLINE | ID: mdl-22285656

Subject(s)

Corpus Striatum/drug effects; Dopamine/metabolism; Neural Inhibition/drug effects; Schizophrenia/drug therapy; Schizophrenia/physiopathology; Sensory Gating/drug effects; 3,4-Dihydroxyphenylacetic Acid/metabolism; Acoustic Stimulation/methods; Animals; Chromatography, High Pressure Liquid; Corpus Striatum/metabolism; Dose-Response Relationship, Drug; Homovanillic Acid/metabolism; Humans; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microdialysis/methods; Neural Inhibition/genetics; Nicotinic Agonists/pharmacology; Quinuclidines/pharmacology; Receptor, Fibroblast Growth Factor, Type 1/deficiency; Receptor, Fibroblast Growth Factor, Type 1/genetics; Reflex, Startle/drug effects; Reflex, Startle/genetics; Schizophrenia/genetics; Sensory Gating/genetics; Thiophenes/pharmacology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Schizophrenia / Dopamine / Corpus Striatum / Sensory Gating / Neural Inhibition Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Schizophr Res Journal subject: PSIQUIATRIA Year: 2012 Document type: Article Affiliation country: United States

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