Colorectal serrated adenocarcinoma shows a different profile of oncogene mutations, MSI status and DNA repair protein expression compared to conventional and sporadic MSI-H carcinomas.

García-Solano, J; Conesa-Zamora, P; Carbonell, P; Trujillo-Santos, J; Torres-Moreno D, D; Pagán-Gómez, I; Rodríguez-Braun, E; Pérez-Guillermo, M

García-Solano, J; Conesa-Zamora, P; Carbonell, P; Trujillo-Santos, J; Torres-Moreno D, D; Pagán-Gómez, I; Rodríguez-Braun, E; Pérez-Guillermo, M.

Affiliation

García-Solano J; Department of Pathology, Santa Lucía General University Hospital (HGUSL), C/Mezquita s/n, 30202 Cartagena, Spain.

Int J Cancer ; 131(8): 1790-9, 2012 Oct 15.

Article in En | MEDLINE | ID: mdl-22287190

Subject(s)

Adenocarcinoma/genetics; Biomarkers, Tumor/genetics; Colorectal Neoplasms/genetics; DNA Repair Enzymes/metabolism; Microsatellite Instability; Microsatellite Repeats/genetics; Mutation/genetics; Adenocarcinoma/metabolism; Adenocarcinoma/mortality; Adenoma/genetics; Adenoma/metabolism; Adenoma/mortality; Aged; Biomarkers, Tumor/metabolism; Class I Phosphatidylinositol 3-Kinases; Colorectal Neoplasms/metabolism; Colorectal Neoplasms/mortality; DNA Methylation; Female; Follow-Up Studies; Humans; Immunoenzyme Techniques; Male; Phosphatidylinositol 3-Kinases/genetics; Prognosis; Proto-Oncogene Proteins/genetics; Proto-Oncogene Proteins B-raf/genetics; Proto-Oncogene Proteins p21(ras); Survival Rate; ras Proteins/genetics

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Colorectal Neoplasms / Adenocarcinoma / Biomarkers, Tumor / Microsatellite Repeats / DNA Repair Enzymes / Microsatellite Instability / Mutation Type of study: Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Aged / Female / Humans / Male Language: En Journal: Int J Cancer Year: 2012 Document type: Article Affiliation country: Spain Country of publication: United States

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google